Vol.18 No.24, June 19, 2025
Seul Koo , Sookhyun Kim
, Myung-Jae Hwang
, So-Young Park
, Youkyoung Kim
, Sang Yun Cho
Objectives: This surveillance report aimed to analyze the characteristics of water- and food-borne outbreaks reported in Daegu Metropolitan City and Gyeongsangbuk-do from 2023 to 2024, and to provide data to support infectious disease prevention and response strategies.
Methods: Outbreak data reported through the national disease surveillance system were analyzed, focusing on outbreak scale, locations, identified pathogens, and sources of infection.
Results: A total of 123 outbreaks were reported over the 2-year period, with 40 in Daegu Metropolitan City and 83 in Gyeongsangbuk-do. The incidence per 100,000 persons was higher in Gyeongsangbuk-do (19.7 cases per 100,000) than in Daegu (17.4 cases per 100,000). In Daegu Metropolitan City, most outbreaks occurred in educational facilities (37.5%), whereas in Gyeongsangbuk-do, restaurants were the most common setting (59.0%). Seasonally, 42.5% and 28.9% of outbreaks in Daegu Metropolitan City and Gyeongsangbuk-do occurred in winter (December–February) and summer (June–August), respectively, indicating a relatively higher seasonal occurrence; however, sporadic cases were observed throughout the year without strong seasonal concentrations. Of the pathogens identified in 67.5% of outbreaks, norovirus was the most common agent in both regions.
Conclusions: The findings indicated that water- and food-borne disease outbreaks in Daegu Metropolitan City and Gyeongsangbuk-do were not limited to specific seasons or settings, highlighting the need to maintain seasonal response strategies while strengthening year-round surveillance and response systems.
Glycogen storage disease (GSD) is a hereditary metabolic disorder caused by defective enzymes involved in carbohydrate metabolism. GSD leads to abnormal glycogen accumulation in tissues, such as the liver, muscles, and heart, resulting in various clinical symptoms, including hypoglycemia, hepatomegaly, muscle weakness, and heart dysfunction. There are several types of GSD. Each type of GSD is caused by a deficiency of a specific enzyme, and its clinical symptoms can vary significantly depending on the affected enzyme and organ systems. Advances in molecular genetics have elucidated the genetic basis of GSD, improving its diagnostic accuracy, and enhancing our understanding of its pathophysiology. This review focused on the molecular mechanisms, clinical symptoms, diagnostic approaches, and current treatment strategies for all types of GSD, including dietary management, enzyme replacement therapy, and emerging genetic therapies. It also addressed challenges relating to treatment adherence, long-term outcomes, and future research directions. Early diagnosis and personalized treatment plans are essential for improving the prognosis of patients with GSD. Continued research to discover more effective treatment options, and ultimately, cure the disease is crucial.
Myung-Jae Hwang, So Yeon Park, Hyungjun Kim, Se Jeong Yang, Sungchan Yang, Jin Seon Yang
Public Health Weekly Report 2025;18: 17-32 https://doi.org/10.56786/PHWR.2025.18.1.2Hyewook Hwang, Wookeon Lee, Seohyeon Ahn, Young-Sook Choi, Seunghyun Lewis Kwon, Dongwoo Lee, Eun Hwa Choi, SokGoo Lee
Public Health Weekly Report 2025;18: 90-102 https://doi.org/10.56786/PHWR.2025.18.2.3+82-43-719-7569