Vol.16 No.6, February 16, 2023
In Sook Shin, Ho Seon Lee, Jeong Ran Kwon, Ji Yeon Lee, Hyang Seon Kim, Kyung Won Hwang*
Public Health Weekly Report 2023; 16(6): 155-170 https://doi.org/10.56786/PHWR.2023.16.6.1Creutzfeldt–Jakob disease (CJD) is transmitted by pathogenic substances called prions and can rapidly lead to death. However, no specialized treatment (medicine) has been developed to date. The route of infection is classified into sporadic (sCJD), iatrogenic, genetic forms ( gCJD), and variant (vCJD). sCJD accounts for 85–90%, while gCJD accounts for 10–15%. CJD was managed through infectious disease surveillance based on the Infectious Disease Prevention and Control Act. In 2011, the monitoring method was changed to a total surveillance system. From 2017 to 2021, 276 patients had probable CJD in the Republic of Korea. Of the total cases, CJD was diagnosed in 35%, and the incidence was higher in patients aged 60–70 years. Of 276 patients, 150 were women (54.3%) and 126 were men (45.7%), with more women than men by 8.6%. For sCJD, the incidence was 92.6% higher in those aged ≥50 years than that in those <50 years old, and for gCJD, the incidence was 54.2% higher in those aged ≥50 years. Upon analysis of the incidence of cases by CJD type and age groups above 50 and under, a significant difference (p<0.05) was observed. From 2017 to 2021, the incidence of CJD by type was 87.0% for sCJD and 13.0% for gCJD, with an incidence of 0.1 per 100,000 people. There was no domestic occurrence of vCJD.
Su jeong Ahn, Hyun Yeong Kim, Min Joon Kim, Jae Sun Park, Gab Jung Kim*
Public Health Weekly Report 2023; 16(6): 171-181 https://doi.org/10.56786/PHWR.2023.16.6.2The Korea Disease Control and Prevention Agency (KDCA) is responsible for conducting and analyzing rapid and accurate diagnostic tests, and monitoring of pathogens that cause infectious diseases. We are developing a Standard Operating Procedure (SOP) that documents the specifications of the laboratory testing environment, and that outlines a certification system for preparing standard test methods. Based on scientific evidence, the SOP describes the background of test selection, sample types, procedures, and results interpretation. An objectively valid and reliable standard inspection method is being prepared through a certification examination committee composed of internal and external experts. The KDCA will continue to revise and update existing certified standard procedures. In addition, we will act preemptively to prepare for and respond to national crises caused by emerging infectious diseases in the future.
Myung-Jae Hwang, So Yeon Park, Hyungjun Kim, Se Jeong Yang, Sungchan Yang, Jin Seon Yang
Public Health Weekly Report 2025;18: 17-32 https://doi.org/10.56786/PHWR.2025.18.1.2Hyewook Hwang, Wookeon Lee, Seohyeon Ahn, Young-Sook Choi, Seunghyun Lewis Kwon, Dongwoo Lee, Eun Hwa Choi, SokGoo Lee
Public Health Weekly Report 2025;18: 90-102 https://doi.org/10.56786/PHWR.2025.18.2.3+82-43-719-7569