PHWR Public Health Weekly Report

Vol.15 No.35, September 01, 2022 Article TypeNoncommunicable Disease StatisticsReview & Perspective

• Review & Perspective 2022-09-01

  0 1350 262

  Management of Young-onset Type 2 Diabetes

  Jae Hyun Bae*

  Public Health Weekly Report 2022; 15(35): 2474-2481 https://doi.org/10.56786/PHWR.2022.15.35.2474

  Abstract

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  The incidence and prevalence of young-onset ( aged <40 years) type 2 diabetes are increasing globally. Accumulating evidence suggests that people with young-onset type 2 diabetes have a more aggressive phenotype, with the development of microvascular and macrovascular complications at an early age and premature mortality, compared to those with usualonset or late-onset type 2 diabetes and type 1 diabetes. The rapid deterioration of pancreatic beta-cell function combined with insulin resistance characterizes the pathophysiology of young-onset type 2 diabetes. Modifiable and non-modifiable risk factors, including intrauterine environment, a longer duration of the disease, and traditional cardiovascular risk factors contribute to disease progression and adverse health outcomes. An increase in young-onset type 2 diabetes may impose a considerable disease burden. Therefore, the early recognition of people at risk and effective strategies to prevent or delay the course of young-onset type 2 diabetes are needed.

• Noncommunicable Disease Statistics 2022-09-01

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  Cardio-Cerebrovascular Disease Mortality Trends, 2009-2020

  Public Health Weekly Report 2022; 15(35): 2482-2483 https://doi.org/10.56786/PHWR.2022.15.35.2482

  

  

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